Clinical Investigation Center - Besançon - COMUE Université Bourgogne-Franche-Comté

Clinical Investigation Center – Besançon

The Clinical Investigation Center of the Besançon University Hospital (Inserm CIC-1431) is accredited by Inserm and the DGOS for its activities in Biotherapy and Technological Innovation. Together with the DRCI, it leads the clinical research of the Besançon University Hospital by supporting, through its different platforms, all the stages of research from the design of protocols to their valorization.

The quality of the CIC’s scientific program is based on local strengths and specific features:

The “Biotherapy” module is the clinical interface of the UMR-1098 Inserm / EFS BFC / UFC, in partnership with the EFS, and the research teams of the University of Franche-Comté. Its objective is to promote the implementation of clinical trials testing innovative therapy drugs (ITDs) and blood-derived products and thus to provide logistical and technical support for designing and carrying out biomedical research projects involving humans in the fields of cell therapy, gene therapy, vaccinology, transplantation and immunotherapy. Thanks to the integration of the Biomonitoring Platform, research projects in biotherapy benefit from a real continuity and complementary nature between clinical investigation and immunomonitoring.

The “Technological Innovation” module has been developed in the field of microtechnology for health in close collaboration with the FEMTO-ST Institute (UMR CNRS 6174) and the regional industrial world.

Three orientations are favored in relation to local strengths: “microtechnologies and instrumentation” in collaboration with FEMTO-ST; “technologies for health in neuropsychiatry” with the support of the neuroscience team; “ethics and medical progress” in collaboration with the Espace Ethique Bourgogne-Franche-Comté and the MSHE (USR CNRS 3124). It is a major player in the emergence of innovations, working with all the medical and surgical services of the University Regional Hospital and the industrial world, thanks in particular to a unique platform dedicated to the evaluation of medical devices.

The Medical Progress and Societal Evolution Axis: newly integrated into the CIC-1431, which is at the interface of the Chrono-Environment UMR and the “Prognostic markers and regulatory factors of cardiac and vascular pathologies” and “Epithelial functions and dysfunctions” teams, around two main themes: infectious risk & environmental microbiology; cardio-neuro-vascular risk.

The CIC is developing a scientific policy based on synergy between the accredited research units, the academic world, the hospital world and the industrial world, on a regional, national and international scale. Through its involvement in various activities (seminars, scientific days, congresses, trade fairs, invited conferences), or training (e.g. double training of biomedical engineers at the ISIFC, master’s degree in neuroscience, master’s degree in Host-Graft Relationship), the CIC actively prepares the professionalization of clinical research actors, particularly in its fields of intervention. The CIC is involved in national thematic networks (CIC-IT, I-REIVAC, Tech-4-Health, Neuroscience, Gynecology) which allows it to rapidly rally the necessary actors for large-scale projects. It is also involved in various European/international projects (R-Link, Eurodesa, etc.).