Lipoproteins have been extensively studied in the cardio-vascular field. In the 1950’s, the transport of cholesterol by lipoproteins was an attractive research topic. LDLs were identified as a major risk factor, while numerous epidemiological works highlighted the “protective” role of HDLs.
The involvement and function of lipoproteins in cancer and inflammatory diseases was only evidenced recently. LDLs and HDLs are also prognostic factors of cancers or certain inflammatory or infectious diseases. These recent findings have brought about an increasing interest in lipoproteins.
The use of these molecular complexes to prevent, diagnose or treat cancer and inflammatory diseases mobilises and federates the LIPSTIC Labex teams.